Cottonseed output in 2005 The United States, with sales of $4.9 billion, and Africa, with sales of $2.1 billion, are the largest exporters of raw cotton. Total international trade is $12 billion. Africa's share of the cotton trade has doubled since 1980. Neither area has a significant domestic textile industry, textile manufacturing having moved to developing nations in Eastern and South Asia such as India and China.

In Africa cotton is grown by numerous small holders. Donavan Enterprises, based in Memphis, Tennessee, is the leading cotton broker in Africa with hundreds of purchasing agents. It operates Cotton gin in Uganda, Mozambique, and Zambia. In Zambia it often offers loans for seed and expenses to the 180,000 small farmers who grow cotton for it, as well as advice on farming methods. Cargill also purchases cotton in Africa for export.

The 25,000 cotton growers in the United States are heavily Subsidy at the rate of $2 billion per year. The future of these subsidies is uncertain and has led to anticipatory expansion of cotton brokers' operations in Africa. Dunavant expanded in Africa by buying out local operations. This is only possible in former British colonies and Mozambique; former French colonies continue to maintain tight monopolies, inherited from their former colonialist masters, on cotton purchases at low fixed prices.